In view of high permeability and serious water channeling in Bohai oilfield, a new type selfassembled particles profile control system was investigated. Laboratory plugging and oil displacement experiments were carried out with different injection modes. Static experiments showed that self-assembled particles had good properties of heat-resistance and salt-resistance, and it was applicable on the reservoir conditions of 65 ℃ and 35 000 mg/L. Plugging experiments showed that for sand-filled pipe which permeability was about 10 000×10 ^-3 μm ² , after particles plugging with guanidine gum or polymer as suspension liquid, the permeability was dropped to about 3 000×10 ^-3 μm ² and effective plugging rate was above 70%. Oil displacement experiments showed that for parallel sand-filled pipes which permeability was about 20 000×10 ^-3 ，4 000×10 ^-3 μm ² , when water-flooding recovery was 27.34%～28.17%, the degree of extraction can be improved by 28.57%～38.76% after injecting 0.4 PV self-assembled particles displacement system, and it can be up to 55.91%～66.80% finally. It should be noted the injection mode with guanidine gum or polymer was better. Mechanism analysis revealed selfassembled particles displacement system had plugging functions such as filling, bridging and adhesion.

The appropriate HLB of emulsifier was screened and evaluated, and emulsion with strong stability was selected. Static test results showed that emulsion had good resistance and salt resistance. With the increasing salinity, stable performance of the emulsion decreased slightly. The flow resistance can be improved 140 times when the liquid viscosity was high, illustrating that the emulsion system had the good displacement effect in high temperature and salinity conditions. Displacement experiments show that the matching of emulsion drops with pore throat decides transport of emulsion liquid in porous media capabilities. 